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Devaux et al. Vital Care (2015) 19:fifty four DOI ten.1186/s13054-015-0767-REVIEWOpen AccessMicroRNAs: new biomarkers and therapeutic targets following cardiac arrest?Yvan Devaux1*, Pascal Stammet2, Hans Friberg3, Christian Hassager4, Michael A Kuiper5, Matt P Wise6, Niklas Nielsen7 and with the Biomarker subcommittee in the TTM trial (Target Temperature Management Following Cardiac Arrest, NCT01020916)unpredictable as well as use of muscle mass paralysis may perhaps confound prognostication [1]. Right up until lately, clinical neurological assessment and neurophysiological checks executed a number of days after the arrest ended up the most effective indicators of result [2,3]. Using circulating biomarkers such as neuron-specific enolase (NSE) improves consequence prediction with a team basis and it has been proposed in scientific exercise [4,5]. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25596739 On the other hand, the discriminative potential of such exams is sub-optimal in unique individuals and administration of individuals could likely advantage from new biomarkers. Learned in 2001 in Caenorhabditis elegans [6-8], microRNAs (miRNAs) have captivated excellent desire inside the scientific group. The discovery in their presence and stability inside the bloodstream [9,10] uncovered the.